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Article

Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains.

Structure (London, England : 1993) - 1 Jul 2004

Botuyan Maria Victoria E, Nominé Yves, Yu Xiaochun, Juranic Nenad, Macura Slobodan, Chen Junjie, Mer Georges

Abstract excerpt

BRCT tandem domains, found in many proteins involved in DNA damage checkpoint and DNA repair pathways, were recently shown to be phosphopeptide binding motifs. Using solution nuclear magnetic resonance (NMR) spectroscopy and mutational analysis, we have characterized the interaction of BRCA1-BRCT...

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Source

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Identifiers

PMID: 15242590
DOI: 10.1016/j.str.2004.06.002
PMCID: PMC3652423

Genes

BRCA1
BACH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15242590-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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