Article
p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions.
Carcinogenesis - 1 Nov 2004
Xi Ya-Guang, Ding Ke-Yue, Su Xiu-Lan, Chen Da-Fang, You Wei-Cheng, Shen Yan, Ke Yang
Abstract excerpt
The development of intestinal gastric carcinoma involves several precancerous stages. The environmental factor plays an important role in gastric carcinogenesis, while the host's genetic makeup may influence the susceptibility to cancer. In this study we investigated correlations of the p53 variations at codon 72 and p21(WAF1/CIP1) haplotype with the risk of intestinal gastric carcinoma. Forty-eight intestinal...
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