Article
Enhanced fructose oxidase activity in a galactose oxidase variant.
Chembiochem : a European journal of chemical biology - 5 Jul 2004
Deacon Sarah E, Mahmoud Khaled, Spooner R Kate, Firbank Susan J, Knowles Peter F, Phillips Simon E V, McPherson Michael J
Abstract excerpt
Galactose oxidase (GO; EC 1.1.3.9) catalyses the oxidation of a wide range of primary alcohols including mono-, oligo- and polysaccharides. High-resolution structures have been determined for GO, but no structural information is available for the enzyme with bound substrate or inhibitor. Previously, computer-aided docking experiments have been used to develop a plausible model for interactions between GO and the...
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