Article
Affected sib-pair analysis of the contribution of HLA class I and class II loci to development of cervical cancer.
Human molecular genetics - 1 Sept 2004
Engelmark Malin, Beskow Anna, Magnusson Jessica, Erlich Henry, Gyllensten Ulf
Abstract excerpt
Cervical cancer is a multifactorial disease and infection by oncogenic human papilloma viruses represents the main environmental risk factor. Only a subset of infections becomes persistent and develops into cancer, implying that genetic susceptibility factors are needed for malignant progression. Here, we use a population-based cohort of affected sib-pairs (ASPs) to examine the role of the human leukocyte antigen...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
