Article
Alterations of APC, c-met, and p53 genes in tumor tissue and serum of patients with gastric cancers.
The Journal of surgical research - 1 Aug 2004
Wang Jaw-Yuan, Hsieh Jan-Sing, Chen Chung-Chi, Tzou Wen-Shyong, Cheng Tien-Lu, Chen Fang-Ming, Huang Tsung-Jen, Huang Yu-Sheng, Huang Sung-Yu, Yang Tzufeng, Lin Shiu-Ru
Abstract excerpt
BACKGROUND: Gastric cancer is one of the most significant causes of cancer-related death worldwide. A genetic model consisting of sequential accumulations of alterations in specific genes for gastric cancer has been proposed. MATERIALS AND METHODS: The significance of adenomatous polyposis coli (APC) and p53 gene mutations in cancer tissues and their paired serum of 34 gastric cancer patients was investigated...
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