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Article

Adaptive changes in bacteria: a consequence of nonlinear transitions in chromosome topology?

Journal of theoretical biology - 7 Aug 2004

Amzallag G N

Abstract excerpt

Adaptive changes in bacteria are generally considered to result from random mutations selected by the environment. This interpretation is challenged by the non-randomness of genomic changes observed following ageing or starvation in bacterial colonies. A theory of adaptive targeting of sequences for enzymes involved in DNA transactions is proposed here. It is assumed that the sudden leakage of cAMP consecutive to...

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Identifiers

PMID: 15234203
DOI: 10.1016/j.jtbi.2004.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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