Intrinsically driven changes in gene interaction complexity. I. Growth of regulatory complexes and increase in number of genes.

Abstract excerpt

A two-step process, previously considered in the literature, and here named coadaptational drive, is deemed to be largely responsible for both increases in the complexity of transcriptional control and increases in the total gene number, along lines of descent leading to more complex organisms. Coadaptational drive consists in a succession of modifications in the interaction among informational macromolecules,...

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