Article
Virus-Host Interaction Gets Curiouser and Curiouser. PART I: Phage P1vir Enhanced Development in an E. coli DksA-Deficient Cell.
International journal of molecular sciences - 31 May 2021
Cech Grzegorz M, Kloska Anna, Krause Klaudyna, Potrykus Katarzyna, Cashel Michael, Szalewska-Pałasz Agnieszka
Abstract excerpt
Bacteriophage P1 is among the best described bacterial viruses used in molecular biology. Here, we report that deficiency in the host cell DksA protein, an E. coli global transcription regulator, improves P1 lytic development. Using genetic and microbiological approaches, we investigated several aspects of P1vir biology in an attempt to understand the basis of this phenomenon. We found several minor improvements...
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