Article
A mutation of the glucocorticoid receptor gene in patients with systemic lupus erythematosus.
The Tohoku journal of experimental medicine - 1 Jun 2004
Lee Young Moo, Fujiwara Junko, Munakata Yasuhiko, Ishii Tomonori, Sugawara Akira, Kaku Mitsuo, Kokubun Shoichi, Sasaki Takeshi, Funato Tadao
Abstract excerpt
We screened for mutations of the glucocorticoid receptor (GR) gene in patients with systemic lupus erythematosus (SLE), a typical autoimmune disease. Polymerase chain reaction-single-strand conformation polymorphism analysis (PCR-SSCP) revealed a single mutation in exon 9 of the GR gene in 11/132...
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