Article
Unravelling the complex genetics of inflammatory bowel disease.
Archives of disease in childhood - 1 Jul 2004
Russell R K, Wilson D C, Satsangi J
Abstract excerpt
The rapid pace of progress in molecular genetics over the past 15 years--since the seminal description of the polymerase chain reaction--has led to the identification of the genes involved in many single gene disorders. These successes in the laboratory have already led directly to clinical applications in diagnosis, pharmacogenetics, and the development of new therapies. Progress in unravelling the genetics of...
Topics
- Carrier Proteins
- Crohn Disease
- Environment
- Genetic Linkage
- Genetic Predisposition to Disease
- Genetic Techniques
- Humans
- Inflammatory Bowel Diseases
- Intracellular Signaling Peptides and Proteins
- Mutation
- Nod2 Signaling Adaptor Protein