Article
Mutations affecting the formation of posterior lateral line system in Medaka, Oryzias latipes.
Mechanisms of development - 1 Jul 2004
Yasuoka Akihito, Hirose Yukihiro, Yoda Hiroki, Aihara Yoshiko, Suwa Hiroshi, Niwa Katsutoshi, Sasado Takao, Morinaga Chikako, Deguchi Tomonori, Henrich Thorsten, Iwanami Norimasa, Kunimatsu Sanae, Abe Keiko, Kondoh Hisato, Furutani-Seiki Makoto
Abstract excerpt
We performed a systematic screen for mutations affecting the trajectory of axons visualized by immunohistochemical staining of Medaka embryos with anti-acetylated tubulin antibody. Among the mutations identified, yanagi (yan) and kazura (kaz) mutations caused specific defects in projection of the posterior lateral line (PLL) nerve. In yan and kaz mutant embryos, the PLL nerve main bundle was misrouted ventrally...
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