Article
Distinct contributions of CXCR4b and CXCR7/RDC1 receptor systems in regulation of PGC migration revealed by medaka mutants kazura and yanagi.
Developmental biology - 15 Aug 2008
Sasado Takao, Yasuoka Akihito, Abe Keiko, Mitani Hiroshi, Furutani-Seiki Makoto, Tanaka Minoru, Kondoh Hisato
Abstract excerpt
Migratory pathways of PGCs to the gonad vary depending on the vertebrate species, yet the underlying regulatory mechanisms guiding PGCs are believed to be largely common. In teleost medaka embryo, PGC migration follows two major steps before colonizing in gonadal areas: (1) bilateral lineup in the trunk and (2) posterior drift of PGCs. kazura (kaz) and yanagi (yan) mutants of medaka isolated in mutagenesis...
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