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Article

Identification of genes that regulate a left-right asymmetric neuronal migration in Caenorhabditis elegans.

Genetics - 1 Aug 2003

Ch'ng QueeLim, Williams Lisa, Lie Yung S, Sym Mary, Whangbo Jennifer, Kenyon Cynthia

Abstract excerpt

In C. elegans, cells of the QL and QR neuroblast lineages migrate with left-right asymmetry; QL and its descendants migrate posteriorly whereas QR and its descendants migrate anteriorly. One key step in generating this asymmetry is the expression of the Hox gene mab-5 in the QL descendants but not in the QR descendants. This asymmetry appears to be coupled to the asymmetric polarizations and movements of QL and...

Topics

Alleles
Animals
Animals, Genetically Modified
Body Patterning
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cell Lineage
Cell Movement
Ethyl Methanesulfonate
Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Helminth

Genes, Homeobox

Glycoproteins

Helminth Proteins

Homeodomain Proteins

Models, Genetic

Mutagenesis

Mutagens

Source

Open in PubMed Open full text

Identifiers

PMID: 12930745
DOI: 10.1093/genetics/164.4.1355
PMCID: PMC1462652

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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