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Article

Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer.

Cancer research - 15 Jun 2004

Sunaga Noriaki, Miyajima Kuniharu, Suzuki Makoto, Sato Mitsuo, White Michael A, Ramirez Ruben D, Shay Jerry W, Gazdar Adi F, Minna John D

Abstract excerpt

Caveolin-1 (CAV1), an essential structural constituent of caveolae that plays an important role in cellular processes such as transport and signaling, has been implicated in the development of human cancers. However, it is unclear whether CAV1 is acting like an oncogene or tumor suppressor gene. We found that CAV1 expression was reduced or absent in 95% of small cell lung cancers (SCLCs; n = 21 lines), whereas it...

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PMID: 15205342
DOI: 10.1158/0008-5472.CAN-03-3941

Genes

CAV1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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