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Article

CAVEOLIN-1 expression in brain metastasis from lung cancer predicts worse outcome and radioresistance, irrespective of tumor histotype.

Oncotarget - 6 Oct 2015

Duregon Eleonora, Senetta Rebecca, Pittaro Alessandra, Verdun di Cantogno Ludovica, Stella Giulia, De Blasi Pierpaolo, Zorzetto Michele, Mantovani Cristina, Papotti Mauro, Cassoni Paola

Abstract excerpt

Brain metastases develop in one-third of patients with non-small-cell lung cancer and are associated with a dismal prognosis, irrespective of surgery or chemo-radiotherapy. Pathological markers for predicting outcomes after surgical resection and radiotherapy responsiveness are still lacking. Caveolin 1 has been associated with chemo- and radioresistance in various tumors, including non-small-cell lung cancer....

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Identifiers

PMID: 26315660
DOI: 10.18632/oncotarget.4988
PMCID: PMC4745751

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