Article
Characterization of the histo-blood group O(2) gene and its protein product.
Vox sanguinis - 1 Jan 2000
Amado M, Bennett E P, Carneiro F, Clausen H
Abstract excerpt
BACKGROUND AND OBJECTIVES: This study aimed to show the full sequence and function of the O(2) allele, and investigate whether it accounts for the incompatible expression of A antigens in gastric carcinomas of blood group O persons. MATERIALS AND METHODS: By PCR, we determined the ABO genotype of group O subjects (76 gastric carcinoma patients and 165 blood donors). Two expression constructs, encoding either the...
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