Article
Why do older women have poor implantation rates? A possible role of the mitochondria.
Journal of assisted reproduction and genetics - 1 Mar 2004
Bartmann Ana Karina, Romão Gustavo Salata, Ramos Ester da Silveira, Ferriani Rui Alberto
Abstract excerpt
Mitochondria are organelles responsible for oxidative phosphorylation, the main energy source for all eukaryotic cells. In oocytes and embryos, it seems that mitochondria provide sufficient energy for fecundation by supporting spindle formation during meiosis II, and for implantation. Since mitochondria are inherited from mother to child, it is important that oocyte mitochondria should be intact. Older women seem...
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