Article
Genetic polymorphism in Mycobacterium tuberculosis isolates from patients with chronic multidrug-resistant tuberculosis.
The Journal of infectious diseases - 1 Jul 2004
Post Frank A, Willcox Paul A, Mathema Barun, Steyn Lafras M, Shean Karen, Ramaswamy Srinivas V, Graviss Edward A, Shashkina Elena, Kreiswirth Barry N, Kaplan Gilla
Abstract excerpt
Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem because treatment is complicated, cure rates are well below those for drug-susceptible tuberculosis (TB), and patients may remain infectious for months or years, despite receiving the best available therapy. To gain a better understanding of MDR-TB, we characterized serial isolates recovered from 13 human immunodeficiency virus-negative...
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