Article
Systematic molecular characterization of multidrug-resistant Mycobacterium tuberculosis complex isolates from Spain.
Journal of clinical microbiology - 1 Mar 2005
Samper S, Iglesias M J, Rabanaque M J, Gómez L I, Lafoz M C, Jiménez M S, Ortega A, Lezcano M A, Van Soolingen D, Martín C
Abstract excerpt
We used spoligotyping and restriction fragment length polymorphism (RFLP) of the IS6110-insertion sequence to study the molecular epidemiology of multidrug-resistant (MDR) tuberculosis in Spain. We analyzed 180 Mycobacterium tuberculosis complex isolates collected between January 1998 and December 2000. Consecutive isolates from the same patients (n = 23) always had identical genotypes, meaning that no cases of...
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