Article
A microarray screen for novel candidate genes in coeliac disease pathogenesis.
Gut - 1 Jul 2004
Diosdado B, Wapenaar M C, Franke L, Duran K J, Goerres M J, Hadithi M, Crusius J B A, Meijer J W R, Duggan D J, Mulder C J J, Holstege F C P, Wijmenga C
Abstract excerpt
BACKGROUND AND AIMS: The causative molecular pathways underlying the pathogenesis of coeliac disease are poorly understood. To unravel novel aspects of disease pathogenesis, we used microarrays to determine changes in gene expression of duodenal biopsies. METHODS: cDNA microarrays representing 19 200 genes were used to compare gene expression profiles of duodenal biopsies from 15 coeliac disease patients with...
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