Article
A t(1;9)(q23.3 approximately q25;q34) affecting the ABL1 gene in a biphenotypic leukemia.
Cancer genetics and cytogenetics - 1 Jul 2004
González García Juan Ramón, Bohlander Stefan K, Gutiérrez Angulo Melva, Esparza Flores María Amparo, Picos Cárdenas Verónica Judith, Meza Espinoza Juan Pablo, Ayala Madrigal María de la Luz, Rivera Horacio
Abstract excerpt
Recurring chromosome translocations, which are found in leukemia, can result in the inappropriate expression of oncogenes or in the formation of chimeric genes that code for structurally and functionally abnormal proteins. The chromosomal t(1;9)(q23.3 approximately q25;q34) was found in a patient with biphenotypic leukemia. Fluorescence in situ hybridization (FISH) analysis revealed that the break on chromosome 9...
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