Article
Non-peptidic HIV protease inhibitors.
Current topics in medicinal chemistry - 1 Jan 2004
Chrusciel R Alan, Strohbach Joseph W
Abstract excerpt
The past decade has seen many exciting achievements and advances in the treatment of HIV infection. One of the key components in this ever-evolving remedial strategy has been medicinally efficacious enzymatic inhibitors targeting the essential viral aspartyl protease. While the use of currently approved HIV protease inhibitors in concert with drugs that target the reverse transcriptase has dramatically...
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