Article
A comparison of the exponential decay slope between PEG-IFN alfa-2b/ribavirin and IFN alfa-2b/ribavirin combination therapy in patients with chronic hepatitis C genotype 1b infection and a high viral load.
Intervirology - 1 Jan 2004
Izumi Namiki, Asahina Yasuhiro, Kurosaki Masayuki, Uchihara Masakatsu, Nishimura Yuki, Inoue Kazunari, Ueda Ken, Tsuchiya Kaoru, Hamano Kousei, Itakura Jun, Miyake Shozo
Abstract excerpt
OBJECTIVES: A high virological response rate can often be shown to be obtained with PEG-IFN alpha-2b and ribavirin combination therapy in chronic hepatitis C patients. Viral dynamics have been utilized for the evaluation of antiviral effects, especially the exponential second decay slope, which represents the elimination of infected cells. METHODS: Forty-nine patients were randomly assigned to the IFN alpha-2b...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.