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Infection of Human Cells by Dengue Virus Is Modulated by Different Cell Types and Viral Strains

1 Sept 2000

Abstract excerpt

Although prior studies have investigated cellular infection by dengue virus (DV), many have used highly passaged strains. We have reassessed cellular infection by DV type 2 (DV2) using prototype and low-passage isolates representing genotypes from different geographic areas. We observed marked variation in the susceptibility to infection among cell types by different DV2 strains. HepG2 hepatoma cells were...

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PMID: 10933688
DOI: 10.1128/jvi.74.17.7814-7823.2000

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