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Article

Identification of Novel Target Genes of the Bone-Specific Transcription Factor Runx2

1 Jun 2004

Abstract excerpt

INTRODUCTION: The transcription factor Runx2 is a key regulator of osteoblast development and plays a role in chondrocyte maturation. The identification of transcriptional target genes of Runx2 may yield insight into how osteoblastic differentiation is achieved on a molecular level. MATERIALS AND METHODS: Using a differential hybridization technique (selective amplification through biotin and restriction-mediated...

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PMID: 15190888
DOI: 10.1359/jbmr.2004.19.6.959

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