Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Screening for the breast cancer gene (BRCA1) using a biochip system and molecular beacon probes immobilized on solid surfaces.

Journal of biomedical optics - 1 Jan 2000

Culha Mustafa, Stokes David L, Griffin Guy D, Vo-Dinh Tuan

Abstract excerpt

We describe the use of a biochip based on complementary metal oxide semiconductor (CMOS) technology for detection of specific genetic sequences using molecular beacons (MB) immobilized on solid surfaces as probes. The applicability of this miniature detection system for screening for the BRCA1 gene is evaluated using MB probes, designed especially for the BRCA1 gene. MB probes are immobilized on a zeta-probe...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adsorption
Share to Biosensing Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to Membranes, Artificial

Share to Oligonucleotide Array Sequence Analysis

Share to Oligonucleotide Probes

Share to Sensitivity and Specificity

Share to Spectrometry, Fluorescence

Source

Identifiers

PMID: 15189080
DOI: 10.1117/1.1691025

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Screening for the breast cancer gene (BRCA1) using a biochip system and molecular beacon probes immobilized on solid surfaces.PMID 15189080Read ↗

Improved DNA microarray detection sensitivity through immobilization of preformed in solution streptavidin/biotinylated oligonucleotide conjugates.Semantic proximity Read ↗

Rolling circle amplification of DNA immobilized on solid surfaces and its application to multiplex mutation detection.Semantic proximity Read ↗

New, fast and cheap prediction tests for BRCA1 gene mutations identification in clinical samples.Semantic proximity Read ↗

Plasmonics nanoprobes: detection of single-nucleotide polymorphisms in the breast cancer BRCA1 gene.Semantic proximity Read ↗

Microbead device for isolating biotinylated oligonucleotides for use in mass spectrometric analysis.Semantic proximity Read ↗

Microarray-based detection of Korean-specific BRCA1 mutations.Semantic proximity Read ↗

Experimental Comparison in Sensing Breast Cancer Mutations by Signal ON and Signal OFF Paper-Based Electroanalytical Strips.Semantic proximity Read ↗

[Analysis of point mutations in BRCA1 gene using hybridization on hydrogel microchips].Semantic proximity Read ↗

Electronic hybridization detection in microarray format and DNA genotyping.Semantic proximity Read ↗

High-capacity and high-intensity DNA microarray spots using oxygen-plasma nanotextured polystyrene slides.Semantic proximity Read ↗

Gold nanoparticle-based label-free detection of BRCA1 mutations utilizing DNA ligation on DNA microarray.Semantic proximity Read ↗

Construction of label-free electrochemical immunosensor on mesoporous carbon nanospheres for breast cancer susceptibility gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.