Article
[Analysis of genome determinants of virulence and setting-up of a library of full-size genome copies of the attenuated virus strain of the porcine reproductive and respiratory syndrome virus North American type].
Voprosy virusologii - 1 Jan 2000
Grebennikova T V, Zaberezhnyĭ A D, Musienko M I, Mengeling W, Lager K, Aliper T I, Nepoklonov E A
Abstract excerpt
Primary genome structures of 3 variants of the NADC-8 North American virulent strain of porcine reproductive and respiratory syndrome virus (PRRSV) were compared for the purpose of detecting any potential genetic virulence determinants of genus Arterivirus. Apart from the virulent variant, we also investigated the attenuated variant, obtained after 251 passages in cell culture, and the intermediate variant...
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