Article
Construction of tree models for pathogenesis of nasopharyngeal carcinoma.
Genes, chromosomes & cancer - 1 Aug 2004
Huang Zhongxi, Desper Richard, Schäffer Alejandro A, Yin Zhihua, Li Xin, Yao Kaitai
Abstract excerpt
Pathogenesis of nasopharyngeal carcinoma (NPC) is a multistep and multipathway process that cannot be fully explained by a fixed linear progression model. We used distance-based and branching-tree methods to construct more general tree-like models for NPC carcinogenesis from 170 comparative genomic hybridization (CGH) samples previously published in five smaller studies. Imbalances were classified into "overlap...
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