Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization

doi:10.1002/1098-2264(2000)9999:9999<::aid-gcc1086>3.0.co;2-d

Article

Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization

1 Jan 2001

Abstract excerpt

To identify genetic alterations associated with the development and progression of human nasopharyngeal carcinoma (NPC), 57 tumors were analyzed by comparative genomic hybridization (CGH). In 47 cases, chromosomal imbalances were found. Several recurrent chromosomal abnormalities were identified in the present study. The most frequently detected chromosomal gains involved chromosome arms 12q (24 cases, 51%), 4q...

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