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Article

Subtype B human immunodeficiency virus (HIV) type 1 mutant that escapes detection in a fourth-generation immunoassay for HIV infection.

Journal of clinical microbiology - 1 Jun 2004

Gaudy Catherine, Moreau Alain, Brunet Sylvie, Descamps Jean-Michel, Deleplanque Pascale, Brand Denys, Barin Francis

Abstract excerpt

We report a case of human immunodeficiency virus (HIV) type 1 infection not detected by a highly sensitive combined antigen-antibody assay. The virus was a subtype B strain harboring a unique sequence within the immunodominant epitope of the transmembrane glycoprotein. Immunochemical analysis indicated that this sequence was probably responsible for the failure to detect HIV antibodies.

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Identifiers

PMID: 15184489
DOI: 10.1128/JCM.42.6.2847-2849.2004
PMCID: PMC427870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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