Article
High levels of discordance between sequencing and serological subtyping in a predominantly non-B subtype HIV-1 infected cohort.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2005
Smith Melvyn, Geretti Anna Maria, Osner Natasha, Easterbrook Philippa, Zuckerman Mark
Abstract excerpt
Samples from 457 randomly selected HIV-1 infected patients attending King's College Hospital were analysed using a subtype specific enzyme immunoassay. All serotyped non-Bs that provided unambiguous sequence and for which sufficient sample was available (n=100), which included three serotyped subtype B samples were further analysed by env sequencing and subtyping using neighbour joining phylogenetic analysis, the...
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