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Article

Genomic characterization of an endemic Mycobacterium tuberculosis strain: evolutionary and epidemiologic implications.

Journal of clinical microbiology - 1 Jun 2004

Nguyen Dao, Brassard Paul, Menzies Dick, Thibert Louise, Warren Rob, Mostowy Serge, Behr Marcel

Abstract excerpt

In a study of 302 Mycobacterium tuberculosis clinical isolates from the low-incidence Canadian-born population of Quebec, we characterized a large endemic strain family by using genomic deletions. The DS6(Quebec) deleted region (11.4 kb) defined a strain family of 143 isolates encompassing two subgroups: one characterized by pyrazinamide (PZA) susceptibility and the other marked by a PZA-monoresistant phenotype....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15184436
DOI: 10.1128/JCM.42.6.2573-2580.2004
PMCID: PMC427889

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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