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Article

Widespread pyrazinamide-resistant Mycobacterium tuberculosis family in a low-incidence setting.

Journal of clinical microbiology - 1 Jul 2003

Nguyen Dao, Brassard Paul, Westley Jennifer, Thibert Louise, Proulx Melanie, Henry Kevin, Schwartzman Kevin, Menzies Dick, Behr Marcel A

Abstract excerpt

An unusually high prevalence of pyrazinamide (PZA) monoresistance in Mycobacterium tuberculosis has been observed in Quebec. In the absence of a recognized outbreak, we hypothesized that these isolates most likely represented reactivation of an old endemic strain in this low-incidence area. A case-control study of 77 PZA-resistant isolates with a specific Quebec mutation and 253 PZA-susceptible control M....

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Identifiers

PMID: 12843016
DOI: 10.1128/JCM.41.7.2878-2883.2003
PMCID: PMC165272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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