Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transport-deficient Pit2 phosphate transporters still modify cell surface oligomers structure in response to inorganic phosphate.

Journal of molecular biology - 25 Jun 2004

Salaün Christine, Maréchal Valérie, Heard Jean Michel

Abstract excerpt

Pit2 is a member of the Pit family of inorganic phosphate transporters and serves as a gamma-retrovirus receptor in mammals. Pit2 contains two copies of the protein homology domain PD001131, which defines the Pit family. These domains are presumably in opposite topology with respect to the plasma membrane plane. We have mutated a serine residue conserved in almost all of the 192 known PD001131 sequences to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Cell Membrane

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CHO Cells

Share to Conserved Sequence

Share to Cricetinae

Share to Leukemia Virus, Murine

Share to Phosphates

Share to Receptors, Virus

Source

Identifiers

PMID: 15184021
DOI: 10.1016/j.jmb.2004.04.050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transport-deficient Pit2 phosphate transporters still modify cell surface oligomers structure in response to inorganic phosphate.PMID 15184021Read ↗

Transmembrane topology of PiT-2, a phosphate transporter-retrovirus receptor.Semantic proximity Read ↗

Evolutionary and experimental analyses of inorganic phosphate transporter PiT family reveals two related signature sequences harboring highly conserved aspartic acids critical for sodium-dependent phosphate transport function of human PiT2.Semantic proximity Read ↗

Structural and mechanistic insights into SLC34 phosphate importSemantic proximity Read ↗

Inorganic phosphate transporters in cancer: Functions, molecular mechanisms and possible clinical applicationsSemantic proximity Read ↗

Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport causing congenital hypophosphatemiaSemantic proximity Read ↗

A broad response to intracellular long-chain polyphosphate in human cellsSemantic proximity Read ↗

Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport and cause congenital hypophosphatemia.Semantic proximity Read ↗

Sodium-dependent phosphate cotransporters: lessons from gene knockout and mutation studies.Semantic proximity Read ↗

Relationship between clinical phenotype and in vitro analysis of 13 NPT2c/SCL34A3 mutants.Semantic proximity Read ↗

TMEM174 Deficiency Reduces Longevity by Promoting Phosphate-Driven Vascular CalcificationSemantic proximity Read ↗

Human Preosteoblastic Cell Culture from a Patient with Severe Tumoral Calcinosis-Hyperphosphatemia Due to a New GALNT3 Gene Mutation: Study of In Vitro Mineralization.Semantic proximity Read ↗

MicroRNA-mediated surveillance of phosphate transporters on the move.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.