Article
The phenotype of sheep hemoglobins containing distinct alpha chains is influenced by beta chain genotype.
Hemoglobin - 1 May 2004
Vestri Rita, Massa Adriana
Abstract excerpt
In sheep carrying simultaneously extra alpha-globin genes (triplications and quadruplications) and two alpha-chain allelic variants, a gradient of decreasing expression of the downstream genes was previously reported. We show here that in these sheep the proportions of the normal and variant Hbs reflect not only the position effect, but also the differential affinity of one of the alpha variants for the betaA and...
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