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Article

Genome-wide identification of genes likely to be involved in human genetic disease.

Nucleic acids research - 1 Jan 2004

López-Bigas Núria, Ouzounis Christos A

Abstract excerpt

Sequence analysis of the group of proteins known to be associated with hereditary diseases allows the detection of key distinctive features shared within this group. The disease proteins are characterized by greater length of their amino acid sequence, a broader phylogenetic extent, and specific conservation and paralogy profiles compared with all human proteins. This unique property pattern provides insights...

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Identifiers

PMID: 15181176
DOI: 10.1093/nar/gkh605
PMCID: PMC434425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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