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Article

Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15.

Circulation - 8 Jun 2004

Sasse-Klaassen Sabine, Probst Susanne, Gerull Brenda, Oechslin Erwin, Nürnberg Peter, Heuser Arnd, Jenni Rolf, Hennies Hans Christian, Thierfelder Ludwig

Abstract excerpt

BACKGROUND: Left ventricular noncompaction (LVNC) is a congenital unclassified cardiomyopathy with numerous prominent trabeculations and deep intertrabecular recesses in a hypertrophied and hypokinetic myocardium. It has been reported to occur in isolation or in association with congenital heart disease. Mutations in the X-linked G4.5 gene are responsible for cases of isolated LVNC in male infants, but G4.5...

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PMID: 15173023
DOI: 10.1161/01.CIR.0000131865.21260.56

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SOX6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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