Article

The genetic architecture of left ventricular non-compaction reveals both substantial overlap with other cardiomyopathies and a distinct aetiology in a subset of cases

2020-01-06

Abstract excerpt

<h4>Background</h4> Left ventricular non-compaction (LVNC) is a condition characterised by trabeculations in the myocardial wall and is the subject of considerable conjecture as to whether it represents a distinct pathology or a secondary phenotype associated with other cardiac diseases, particularly cardiomyopathies. We sought to investigate the genetic architecture of LVNC by identifying genes and variant classe...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 77e586b4-d8b9-513a-b7e7-db0d12abb848
DOI: 10.1101/2020.01.03.19015602

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The genetic architecture of left ventricular non-compaction reveals both substantial overlap with other cardiomyopathies and a distinct aetiology in a subset of casesDOI 10.1101/2020.01.03.19015602Read

Systematic large-scale assessment of the genetic architecture of left ventricular noncompaction reveals diverse etiologiesSemantic proximity Read

Left Ventricular Non-Compaction Cardiomyopathy: A Review of the Pathophysiology, Epidemiology, Diagnosis, Genetics, and Clinical ManagementSemantic proximity Read

Genetic Architecture, Developmental Mechanisms, and Genomic Applications in Left Ventricular Non-Compaction Cardiomyopathy (LVNC)Semantic proximity Read

The Trouble with Trabeculation: How Genetics Can Help to Unravel a Complex and Controversial Phenotype.Semantic proximity Read

Left Ventricular Non-Compaction Cardiomyopathy: A Review of the Pathophysiology, Epidemiology, Diagnosis, Genetics, and Clinical ManagementSemantic proximity Read

Genetic Spectrum of Left Ventricular Non-Compaction in Paediatric Patients.Semantic proximity Read

Targeted panel sequencing in adult patients with left ventricular non‐compaction reveals a large genetic heterogeneitySemantic proximity Read

Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy.Semantic proximity Read

Genetic Analysis of Patients with Left Ventricular Noncompaction: Identification of Novel Candidate VariantsSemantic proximity Read

[Left ventricular non - compaction: contemporary view of genetic background, clinical course, diagnostic and treatment].Semantic proximity Read

Left ventricular non-compaction cardiomyopathy.Semantic proximity Read

Genetic Profile of Left Ventricular Noncompaction Cardiomyopathy in Children—A Single Reference Center ExperienceSemantic proximity Read