Article
Genetic dissection of diseases: design and methods.
Current opinion in genetics & development - 1 Jun 2004
Hoh Josephine, Ott Jurg
Abstract excerpt
The etiology of heritable diseases may be elucidated by localizing genes conferring susceptibility and by subsequent biological characterization of these genes. To localize genetic components for multifactorial traits, both hypothesis-driven candidate gene and hypothesis-free genome scan approaches have been applied. To date, only a handful of results have been reproduced in either a different cohort or model...
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