Article
Interferon-gamma gene dinucleotide (CA) repeat and interleukin-4 promoter region (-590C/T) polymorphisms in Japanese patients with endometriosis.
Human reproduction (Oxford, England) - 1 Aug 2004
Kitawaki Jo, Koshiba Hisato, Kitaoka Yui, Teramoto Mariko, Hasegawa Goji, Nakamura Naoto, Yoshikawa Toshikazu, Ohta Mitsuhiro, Obayashi Hiroshi, Honjo Hideo
Abstract excerpt
BACKGROUND: Endometriosis is a multifactorial disease with possible genetic predisposition and involvement of environmental factors in its pathogenesis. Cytokines may play important roles in the pathogenesis of endometriosis. The aim of this study was to investigate whether the interferon-gamma gene (IFNG) CA-repeat and interleukin-4 (IL-4) promoter region (-590C/T) polymorphisms may be responsible in part for...
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