Article
A novel approach for assessment of cancer predisposing roles of GSTM1 and GSTT1 genes: use of putatively cancer resistant elderly tumor-free smokers as the referents.
Lung cancer (Amsterdam, Netherlands) - 1 Mar 2004
Belogubova Evgeniya V, Togo Alexandr V, Karpova Maria B, Kuligina Ekatherina Sh, Buslova Konstantin G, Ulibina Julia M, Lemehov Vladimir G, Romanenko Sergey M, Shutkin Vladimir A, Hanson Kaido P, Hirvonen Ari, Imyanitov Evgeny N
Abstract excerpt
We applied an alternative approach to assess the controversial evidence for the role of GSTM1 and GSTT1 deficiencies (null genotypes) in cancer susceptibility. In this study setting, the prevalence of GSTM1 and GSTT1 null genotypes in the lung cancer patients (LCs, n = 167) were compared with tho...
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