Article
Detection of 14 alleles derived from the MHC class I A locus in cynomolgus monkeys.
Immunogenetics - 1 Jun 2004
Uda Akihiko, Tanabayashi Kiyoshi, Yamada Yasuko K, Akari Hirofumi, Lee Young-Jung, Mukai Ryozaburo, Terao Keiji, Yamada Akio
Abstract excerpt
A basic understanding of the major histocompatibility complex (MHC) class I, which, together with T-cell receptors, is a key player in antigen recognition by cytotoxic T lymphocytes, is necessary to study the cellular immune response to intracellular pathogens. The MHC has hardly been reported in cynomolgus monkeys ( Macaca facicularis), although cynomolgus monkeys have been frequently used as the surrogate...
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