Article
Multilocus definition of MHC haplotypes in pedigreed cynomolgus macaques (Macaca fascicularis).
Immunogenetics - 1 Oct 2012
Otting Nel, de Groot Nanine, de Vos-Rouweler Annemiek J M, Louwerse Annet, Doxiadis Gaby G M, Bontrop Ronald E
Abstract excerpt
Cynomolgus macaques (Macaca fascicularis) are used widely in biomedical research, and the genetics of their MHC (Mhc-Mafa) has become the focus of considerable attention in recent years. The cohort of Indonesian pedigreed macaques that we present here was typed for Mafa-A, -B, and -DR, by sequencing, as described in earlier studies. Additionally, the DRB region of these animals was characterised by microsatellite...
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