Article
Evidence of recombination producing allelic diversity in MHC class I Mafa-B and -A alleles in cynomolgus macaques.
Tissue antigens - 1 May 2012
Orysiuk D, Lawrence J, Prashar T, Spangelo L, Pilon R, Fournier J, Rud E, Sandstrom P, Plummer F A, Luo M
Abstract excerpt
The MHC class I-A and -B genes of cynomolgus macaques are highly polymorphic. These genes encode proteins presenting peptides to CD8+ T cells to initiate adaptive immune response. Recombination events are one way the diversity of these alleles can be increased. Such events have been well characte...
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