Article
Balance of RNA sequence requirement and NS3/NS3a expression of segment 10 of orbiviruses.
The Journal of general virology - 1 Feb 2016
Feenstra Femke, van Gennip René G P, Schreuder Myrte, van Rijn Piet A
Abstract excerpt
Orbiviruses are insect-transmitted, non-enveloped viruses with a ten-segmented dsRNA genome of which the bluetongue virus (BTV) is the prototype. Viral non-structural protein NS3/NS3a is encoded by genome segment 10 (Seg-10), and is involved in different virus release mechanisms. This protein induces specific release via membrane disruptions and budding in both insect and mammalian cells, but also the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
