Article
Lineage relationship between LNCaP and LNCaP-derived prostate cancer cell lines.
The Prostate - 1 Jul 2004
Liu Alvin Y, Brubaker Kristen D, Goo Young Ah, Quinn Janna E, Kral Sabine, Sorensen Carrie M, Vessella Robert L, Belldegrun Arie S, Hood Leroy E
Abstract excerpt
BACKGROUND: LNCaP and its derivative cell lines, which include C4-2 (and the related C4-2B) and CL1, are used as models of prostate cancer. Unlike LNCaP, the other cell lines show features of progressed disease such as metastatic capability and hormone independence. Analyses were done to determine if C4-2 or CL1 cells were selected from pre-existent subpopulations in LNCaP. METHODS: Prostate cancer cells were...
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