Article
Pathogenic consequences of Neisseria gonorrhoeae pilin glycan variation.
Microbes and infection - 1 Jun 2004
Ghosh Salil K, Zhao Jie, Philogene Mary C, Alzaharani Abdulrahaman, Rane Supriya, Banerjee Asesh
Abstract excerpt
A Neisseria gonorrhoeae (gonococcus, GC) pilin glycosylation gene, pgtA, can either possess or lack phase-variation ability. Many GC, particularly the disseminated strains, carry a phase-variable pgtA. However, other GC, predominantly the uncomplicated gonorrhea isolates, carry a pgtA lacking phase-variability. These and other results suggest GC pilin glycan's pathogenic involvement.
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