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Article

DNA substrate-induced activation of the Agrobacterium VirB/VirD4 type IV secretion system.

Journal of bacteriology - 1 Jun 2013

Cascales Eric, Atmakuri Krishnamohan, Sarkar Mayukh K, Christie Peter J

Abstract excerpt

The bitopic membrane protein VirB10 of the Agrobacterium VirB/VirD4 type IV secretion system (T4SS) undergoes a structural transition in response to sensing of ATP binding or hydrolysis by the channel ATPases VirD4 and VirB11. This transition, detectable as a change in protease susceptibility, is required for DNA substrate passage through the translocation channel. Here, we present evidence that DNA substrate...

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Identifiers

PMID: 23564169
DOI: 10.1128/JB.00114-13
PMCID: PMC3676061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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