Article
Immunohistochemically detectable Cdx2 is present in intestinal phenotypic elements in early gastric cancers of both differentiated and undifferentiated types, with no correlation to non-neoplastic surrounding mucosa.
Pathology international - 1 Jun 2004
Mizoshita Tsutomu, Tsukamoto Tetsuya, Inada Ken-Ichi, Ogasawara Naotaka, Hirata Akihiro, Kato Sosuke, Joh Takashi, Itoh Makoto, Yamamura Yoshitaka, Tatematsu Masae
Abstract excerpt
It has previously been reported that Cdx2 is the useful prognostic and intestinal phenotypic marker in advanced gastric cancers (GC). In this study, Cdx2 expression and phenotype in early GC and non-neoplastic surrounding mucosa were examined. A total of 130 early GC (70 intramucosal and 60 submucosally invasive cancers) histologically and phenotypically were evaluated. The expression of Cdx2 was assessed by...
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