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Transduced caudal‐type homeobox ( CDX ) 2/ CDX 1 can induce growth inhibition on CDX ‐deficient gastric cancer by rapid intestinal differentiation

6 Oct 2018

Abstract excerpt

Intestinal metaplasia induced by ectopic expression of caudal-type homeobox (CDX)2 and/or CDX1 (CDX) is frequently observed around gastric cancer (GC). Abnormal expression of CDX is also observed in GC and suggests that inappropriate gastrointestinal differentiation plays essential roles in gastric tumorigenesis, but their roles on tumorigenesis remain unelucidated. Publicly available databases show that GC...

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PMID: 30289576
DOI: 10.1111/cas.13821

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